Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23311669 | 0.85 | GPR119 (0.67) | GPR119NPBWR1MCHR1 | |
| SCHEMBL13993542 | 0.83 | GPR119 (0.67) | GPR119NPBWR1MCHR1 | |
| SCHEMBL2524108 | 0.83 | GPR119 (0.57) | GPR119PIK3CD | |
| SCHEMBL14941901 | 0.83 | PIK3CA (0.57) | GPR119PIK3CAPIK3CD | |
| SCHEMBL23481129 | 0.83 | GPR119 (0.42) | GPR119PIK3CAPIK3CD | |
| SCHEMBL20137797 | 0.82 | GPR119 (0.67) | GPR119NPBWR1MCHR1 | |
| SCHEMBL20227205 | 0.82 | GPR119 (0.54) | GPR119NPBWR1MCHR1 | |
| SCHEMBL16771170 | 0.81 | GPR119 (0.54) | GPR119PIK3CANPBWR1MCHR1 | |
| SCHEMBL2548353 | 0.81 | GPR119 (0.65) | GPR119NPBWR1MCHR1 | |
| SCHEMBL5267887 | 0.81 | GPR119 (0.68) | GPR119NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122763-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN-CILAG S.A. (ES) | 2021-04-29 | — | — | US | disclosed |
| WO-2019243530-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122763-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | GPR119 1166/4885PIK3CA 1282/4885NPBWR1 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.