Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21607656 | 0.95 | RORC (0.60) | RORC | |
| SCHEMBL21607782 | 0.90 | RORC (0.61) | RORC | |
| SCHEMBL21607501 | 0.88 | RORC (0.61) | RORC | |
| SCHEMBL28530500 | 0.88 | RORC (0.61) | RORC | |
| SCHEMBL21607636 | 0.87 | RORC (0.63) | RORC | |
| SCHEMBL21607428 | 0.86 | RORC (0.60) | RORC | |
| SCHEMBL21607345 | 0.85 | RORC (0.64) | RORC | |
| SCHEMBL28542173 | 0.84 | RORC (0.64) | RORC | |
| SCHEMBL21607791 | 0.83 | RORC (0.43) | RORC | |
| SCHEMBL21607486 | 0.83 | RORC (0.64) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243999-A1 | PHENYL SUBSTITUTED PYRAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |