Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | APLNR | P35414 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21608099 | 1.00 | MAP4K4 (0.33) | MAP4K4HRH3APLNRKCNH2GHSR | |
| SCHEMBL21608093 | 1.00 | MAP4K4 (0.33) | MAP4K4HRH3APLNRKCNH2GHSR | |
| SCHEMBL21608092 | 1.00 | MAP4K4 (0.33) | MAP4K4HRH3APLNRKCNH2GHSR | |
| SCHEMBL21608030 | 0.89 | DRD4 (0.35) | MAP4K4HRH3APLNRGHSR | |
| SCHEMBL21608028 | 0.89 | DRD4 (0.35) | MAP4K4HRH3APLNRGHSR | |
| SCHEMBL21608548 | 0.85 | KDM1A (0.35) | HRH3KCNH2GHSROGAIDH1 | |
| SCHEMBL23868330 | 0.82 | PTGDR2 (0.32) | HRH3OGA | |
| SCHEMBL23868333 | 0.82 | PTGDR2 (0.32) | HRH3OGA | |
| SCHEMBL23868331 | 0.82 | PTGDR2 (0.32) | HRH3OGA | |
| SCHEMBL21608536 | 0.82 | PDE9A (0.35) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |