Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | GHSR | Q92847 | 3/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21608028 | 1.00 | DRD4 (0.35) | DRD4HRH3SLC6A4APLNRCHRM2 | |
| SCHEMBL21608099 | 0.89 | MAP4K4 (0.33) | HRH3APLNRGHSRMAP4K4 | |
| SCHEMBL21608097 | 0.89 | MAP4K4 (0.33) | HRH3APLNRGHSRMAP4K4 | |
| SCHEMBL21608093 | 0.89 | MAP4K4 (0.33) | HRH3APLNRGHSRMAP4K4 | |
| SCHEMBL21608092 | 0.89 | MAP4K4 (0.33) | HRH3APLNRGHSRMAP4K4 | |
| SCHEMBL21608548 | 0.86 | KDM1A (0.35) | HRH3GHSRDGKZACACB | |
| SCHEMBL21608552 | 0.82 | TRPV6 (0.37) | GHSR | |
| SCHEMBL21608569 | 0.82 | TRPV6 (0.37) | GHSR | |
| SCHEMBL21608568 | 0.82 | TRPV6 (0.37) | GHSR | |
| SCHEMBL21608560 | 0.82 | TRPV6 (0.37) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |