SCHEMBL21609138

SCHEMBL21609138

COc1cc(-c2cc(OC)c3c(NSc4c(OC)cccc4OC)noc3c2)ccn1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 18/20 0.39
KAT7 O95251 17/20 0.39
KAT6B Q8WYB5 8/20 0.39
S1PR1 P21453 1/20 0.39
KAT5 Q92993 5/20 0.39
KAT8 Q9H7Z6 5/20 0.39
KCNA5 P22460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609190 0.87 KAT6A (0.41) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609267 0.86 ERN1 (0.39) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609197 0.82 KAT6A (0.39) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609135 0.82 SGMS2 (0.43) KAT6AKAT7KAT6BS1PR1KAT5
SCHEMBL21609078 0.81 KAT6A (0.42) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609069 0.81 KIT (0.40) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609137 0.80 KAT6A (0.63) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL31605642 0.80 KAT6A (0.63) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609061 0.80 KAT6A (0.39) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817426 0.79 KAT6A (0.48) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed