SCHEMBL21609159

SCHEMBL21609159

CCc1ccc(OC)c(S(=O)(=O)Nc2noc3ccc(CN)cc23)c1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 16/20 0.59
KAT7 O95251 15/20 0.59
KAT6B Q8WYB5 10/20 0.59
KAT5 Q92993 7/20 0.55
KAT8 Q9H7Z6 7/20 0.55
ALPL P05186 1/20 0.49
BRD4 O60885 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609167 0.95 KAT6A (0.63) KAT6AKAT7KAT6BKAT5KAT8
Trifluoroacetic Acid SCHEMBL21596837 0.92 KAT6A (0.54) KAT6AKAT7KAT6BKAT5KAT8
Trifluoroacetic Acid SCHEMBL31605566 0.92 KAT6A (0.54) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21596889 0.90 KAT6A (0.59) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21596823 0.89 KAT6A (0.59) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609074 0.89 KAT6A (0.59) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL29652583 0.89 KAT6A (0.59) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609122 0.88 KAT6A (0.59) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21596798 0.88 KAT6A (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL31605586 0.88 KAT6A (0.69) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT6A 877/4885KAT7 490/4885KAT6B 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.