SCHEMBL21609587

SCHEMBL21609587

Oc1cccnc1Cc1ccc(F)c(F)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.49
ALDH1A1 P00352 1/20 0.49
KDM4E B2RXH2 2/20 0.45
HSD17B10 Q99714 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
MPI P34949 1/20 0.40
PARP1 P09874 5/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
KDM5A P29375 1/20 0.39
KDM5B Q9UGL1 1/20 0.39
CYP17A1 P05093 2/20 0.38
CYP11B1 P15538 2/20 0.38
CYP11B2 P19099 2/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1973913 0.75 KDM4E (0.68) L3MBTL1ALDH1A1KDM4EHSD17B10PARP1
SCHEMBL27645370 0.75 PARP1 (0.44) L3MBTL1ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL4853382 0.75 ALDH1A1 (0.53) L3MBTL1ALDH1A1KDM4EHSD17B10CYP1A2
SCHEMBL6136755 0.74 KDM4E (0.49) L3MBTL1ALDH1A1KDM4EHSD17B10PARP1
Hydrochloric Acid SCHEMBL31388648 0.74 KDM4E (0.71) L3MBTL1ALDH1A1KDM4EHSD17B10PARP1
SCHEMBL11018646 0.72 ALDH1A1 (0.50) L3MBTL1ALDH1A1KDM4EHSD17B10CYP1A2
SCHEMBL21609582 0.71 PARP1 (0.38) L3MBTL1ALDH1A1CYP1A2CYP2D6PARP1
SCHEMBL17664392 0.71 PARP1 (0.45) ALDH1A1CYP2D6PARP1CYP2C19KDM5A
SCHEMBL1446035 0.71 ALDH1A1 (0.45) L3MBTL1ALDH1A1KDM4EHSD17B10CYP1A2
SCHEMBL1445774 0.70 KDM4E (0.51) L3MBTL1ALDH1A1KDM4EHSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020002087-A1 SUBSTITUTED 3-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2020-01-02 WO disclosed
WO-2020002087-A1 SUBSTITUTED 3-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2020-01-02 WO disclosed