SCHEMBL21609784

SCHEMBL21609784

O=C(O)c1cc(OC2CC2)cc(OC2CC2)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 10/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KMT2A Q03164 2/20 0.44
FAAH O00519 3/20 0.43
MEN1 O00255 1/20 0.42
PARP10 Q53GL7 1/20 0.42
TPMT P51580 1/20 0.41
GRIK1 P39086 1/20 0.41
GRIA2 P42262 1/20 0.41
PLA2G2A P14555 1/20 0.41
SRD5A1 P18405 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30938042 0.87 KMT2A (0.46) EPHX2ALDH1A1LMNACASP3SENP8
SCHEMBL20462868 0.87 TPMT (0.59) EPHX2ALDH1A1LMNACASP3SENP8
SCHEMBL26146678 0.87 EPHX2 (0.52) EPHX2FAAH
SCHEMBL29952314 0.84 UNG (0.42) EPHX2ALDH1A1LMNACASP3SENP8
SCHEMBL15881613 0.83 EPHX2 (0.48) EPHX2FAAH
SCHEMBL1107609 0.82 ALDH1A1 (0.42) EPHX2ALDH1A1LMNACASP3SENP8
SCHEMBL932285 0.82 KMT2A (0.45) EPHX2KMT2APARP10
SCHEMBL29505911 0.81 EPHX2 (0.65) EPHX2KMT2AMEN1GRIK1GRIA2
SCHEMBL10174911 0.81 KMT2A (0.50) EPHX2ALDH1A1LMNACASP3SENP8
SCHEMBL594232 0.81 KMT2A (0.47) EPHX2KMT2AFAAHPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3814332-B1 PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2023-06-07 EP disclosed
EP-3814332-B1 PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2023-06-07 EP disclosed
EP-3814332-A1 PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-05-05 EP disclosed
WO-2020002563-A1 PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2020-01-02 WO disclosed
WO-2020002563-A1 PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2020-01-02 WO disclosed