Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125265 | 1.00 | AKR1C4 (0.44) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL25669658 | 0.84 | CA12 (0.50) | KDM4EMEN1KMT2ATDP1CA12 | |
| SCHEMBL2226763 | 0.81 | AKR1C3 (0.61) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL29454359 | 0.81 | MYC (0.56) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL286633 | 0.81 | MYC (0.56) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL27091773 | 0.79 | TTR (0.54) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL20503773 | 0.79 | CA12 (0.50) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL20142067 | 0.78 | GAA (0.55) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL31026219 | 0.78 | CYP3A4 (0.52) | KDM4EMEN1KMT2ATDP1CA12 | |
| SCHEMBL89590 | 0.78 | CYP3A4 (0.52) | KDM4EMEN1KMT2ATDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814332-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3814332-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-05 | — | — | EP | disclosed |
| WO-2020002563-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-02 | — | — | WO | disclosed |