Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.32 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.32 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12336846 | 0.92 | MEN1 (0.47) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL1923135 | 0.91 | MEN1 (0.56) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL2161013 | 0.90 | MAPK1 (0.52) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL2315369 | 0.90 | MAPK1 (0.41) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL3699829 | 0.84 | MEN1 (0.47) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL3700015 | 0.81 | MEN1 (0.49) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL2159802 | 0.81 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL3237155 | 0.80 | MAPK1 (0.39) | MEN1KMT2ATDP1HSP90AA1MAPK1 | |
| SCHEMBL1964298 | 0.79 | MEN1 (0.57) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL10915818 | 0.78 | MEN1 (0.51) | MEN1KMT2ATDP1HSP90AA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183842-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | BASF SE (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2346838-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010040718-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183842-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | OAT, ABAT, TYR | MEN1 1942/4885KMT2A 2752/4885TDP1 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.