Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116592 | 0.78 | MAPT (0.62) | MAPTGAATHRBTP53MEN1 | |
| SCHEMBL20116655 | 0.75 | SMN1; SMN2 (0.54) | MAPTGAATHRBTP53MEN1 | |
| SCHEMBL30506255 | 0.74 | MAPT (0.67) | MAPTGAATHRBTP53MEN1 | |
| SCHEMBL20116597 | 0.74 | MAPT (0.67) | MAPTGAATHRBTP53MEN1 | |
| SCHEMBL26998415 | 0.74 | MAPT (0.53) | MAPTGAATHRBTP53MEN1 | |
| Hydrochloric Acid SCHEMBL20661124 | 0.73 | MAPT (0.66) | MAPTGAATHRBTP53MEN1 | |
| SCHEMBL26998422 | 0.72 | SMN1; SMN2 (0.58) | MAPTGAATHRBTP53POLB | |
| SCHEMBL20116601 | 0.72 | MAPT (0.57) | MAPTTHRBTP53MEN1KMT2A | |
| SCHEMBL20116262 | 0.71 | MAPT (0.59) | MAPTGAATHRBTP53MEN1 | |
| SCHEMBL20117011 | 0.71 | MAPT (0.61) | MAPTGAATHRBTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |