Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26998415 | 0.88 | MAPT (0.53) | SMN1; SMN2MAPTGAATHRBMAPK1 | |
| SCHEMBL26998422 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTGAATHRBMAPK1 | |
| SCHEMBL20116262 | 0.86 | MAPT (0.59) | SMN1; SMN2MAPTGAATHRBMAPK1 | |
| SCHEMBL20117011 | 0.85 | MAPT (0.61) | SMN1; SMN2MAPTGAATHRBMAPK1 | |
| SCHEMBL22343934 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTGAATHRBMAPK1 | |
| SCHEMBL20116601 | 0.82 | MAPT (0.57) | SMN1; SMN2MAPTTHRBMAPK1TP53 | |
| SCHEMBL20116135 | 0.76 | MAPT (0.53) | SMN1; SMN2MAPTTHRBTP53ALDH1A1 | |
| SCHEMBL21609974 | 0.75 | MAPT (0.56) | SMN1; SMN2MAPTGAATHRBTP53 | |
| SCHEMBL22358160 | 0.75 | MAPT (0.51) | SMN1; SMN2MAPTTHRBMAPK1TP53 | |
| SCHEMBL20116633 | 0.75 | MAPT (0.51) | SMN1; SMN2MAPTTHRBMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |