Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 13/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419647 | 0.86 | GAA (0.52) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6419651 | 0.86 | GAA (0.52) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL8265099 | 0.81 | MAPT (0.55) | GAAMAPTALDH1A1BIRC5SMN1; SMN2 | |
| SCHEMBL3046026 | 0.80 | BIRC5 (0.53) | GAAMAPTALDH1A1BIRC5SMN1; SMN2 | |
| SCHEMBL6416845 | 0.80 | BIRC5 (0.53) | GAAMAPTALDH1A1BIRC5SMN1; SMN2 | |
| SCHEMBL3046030 | 0.80 | BIRC5 (0.53) | GAAMAPTALDH1A1BIRC5SMN1; SMN2 | |
| SCHEMBL6507461 | 0.75 | BIRC5 (0.67) | GAAMAPTALDH1A1NPSR1BIRC5 | |
| SCHEMBL6507458 | 0.75 | BIRC5 (0.67) | GAAMAPTALDH1A1NPSR1BIRC5 | |
| SCHEMBL13905878 | 0.73 | BIRC5 (0.52) | GAAMAPTALDH1A1NPSR1BIRC5 | |
| SCHEMBL8265004 | 0.73 | GAA (0.56) | GAAMAPTALDH1A1NPSR1BIRC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10517871-B2 | Survivin-targeting anti-tumor agents and uses thereof | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2019-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10517871-B2 | Survivin-targeting anti-tumor agents and uses thereof | XIAP, BIRC5, BIRC2 | GAA 2017/4885MAPT 2699/4885ALDH1A1 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.