Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 14/20 | 0.49 |
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507458 | 1.00 | BIRC5 (0.67) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL6435990 | 0.85 | BIRC5 (0.78) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL8265009 | 0.85 | BIRC5 (0.78) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL6435981 | 0.85 | BIRC5 (0.78) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL8265974 | 0.85 | BIRC5 (0.71) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL6503291 | 0.83 | MET (0.52) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL6506319 | 0.83 | MET (0.52) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL6507634 | 0.82 | MET (0.48) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL6414148 | 0.82 | MET (0.48) | BIRC5MAPTMEN1KMT2APOLB | |
| SCHEMBL6414157 | 0.82 | MET (0.48) | BIRC5MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | 4SC AG (DE) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | NR5A2, NR1H2, NR2C2 | BIRC5 2525/4885MAPT 4420/4885MEN1 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.