Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833879 | 0.85 | SIGMAR1 (0.36) | ESR1KCNH2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1832926 | 0.85 | NR1H3 (0.40) | ESR1KCNH2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1835592 | 0.80 | MEN1 (0.34) | ESR1KCNH2ALDH1A1LMNAPOLB | |
| SCHEMBL1854580 | 0.74 | AVPR2 (0.34) | ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL2161767 | 0.71 | CYP1A2 (0.39) | NPC1CYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL12402747 | 0.70 | ESR1 (0.37) | ESR1KCNH2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2161395 | 0.70 | KDM4E (0.35) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL1834507 | 0.69 | ESR1 (0.36) | ESR1KCNH2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1834307 | 0.69 | SMN1; SMN2 (0.44) | NPC1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1831398 | 0.68 | ESR1 (0.35) | ESR1KCNH2CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | ESR1 3395/4885KCNH2 84/4885NPC1 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.