Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21612863 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL30012531 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL15185722 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL31498738 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL23801147 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL23801148 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL31498681 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL17165584 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL17165585 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL30411459 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |