⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21612899 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL22634307 | 0.68 | KDM4E (0.35) | — | |
| SCHEMBL30628425 | 0.62 | PIM1 (0.33) | — | |
| SCHEMBL22747795 | 0.61 | — | — | |
| SCHEMBL7385004 | 0.59 | TSHR (0.34) | — | |
| SCHEMBL22899184 | 0.59 | — | — | |
| SCHEMBL21612898 | 0.57 | — | — | |
| SCHEMBL28812369 | 0.56 | LMNA (0.31) | — | |
| SCHEMBL20075881 | 0.52 | PREP (0.44) | — | |
| SCHEMBL4276190 | 0.52 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |