Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BRD1 | O95696 | 2/20 | 0.31 |
| ▸ | TAF1 | P21675 | 2/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837952 | 0.89 | GRM1 (0.42) | GRM4LMNASMN1; SMN2GRM1 | |
| SCHEMBL1849927 | 0.89 | LMNA (0.34) | GRM4LMNASMN1; SMN2GRM1MEN1 | |
| SCHEMBL2161650 | 0.89 | MEN1 (0.36) | GRM4GRM1MEN1KMT2A | |
| SCHEMBL2889808 | 0.85 | LMNA (0.38) | GRM4LMNASMN1; SMN2GRM1 | |
| SCHEMBL3327139 | 0.83 | GRM1 (0.40) | GRM4LMNASMN1; SMN2GRM1 | |
| SCHEMBL2889539 | 0.83 | LMNA (0.33) | GRM4LMNASMN1; SMN2GRM1 | |
| SCHEMBL2161154 | 0.83 | GRIA2 (0.39) | GRM4LMNASMN1; SMN2GRM1MEN1 | |
| SCHEMBL5716927 | 0.80 | GRM4 (0.33) | GRM4LMNASMN1; SMN2GRM1 | |
| SCHEMBL2889978 | 0.78 | LMNA (0.33) | GRM4LMNASMN1; SMN2GRM1 | |
| SCHEMBL2889323 | 0.78 | LMNA (0.33) | GRM4LMNASMN1; SMN2GRM1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | GRM4 3660/4885LMNA 1928/4885SMN1; SMN2 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.