Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23103243 | 0.83 | PIK3CD (0.47) | DPP4DPP8DPP9PIK3CD | |
| SCHEMBL12041121 | 0.83 | PIK3CD (0.47) | DPP4DPP8DPP9PIK3CD | |
| SCHEMBL23103231 | 0.83 | PIK3CD (0.47) | DPP4DPP8DPP9PIK3CD | |
| SCHEMBL14738746 | 0.79 | DPP4 (0.40) | DPP4DPP8DPP9PIK3CD | |
| SCHEMBL14738064 | 0.79 | DPP4 (0.40) | DPP4DPP8DPP9PIK3CD | |
| SCHEMBL31483950 | 0.79 | SLC6A3 (0.37) | DPP4DPP8DPP9 | |
| SCHEMBL24616000 | 0.79 | SLC6A3 (0.37) | DPP4DPP8DPP9 | |
| SCHEMBL24616051 | 0.79 | SLC6A3 (0.37) | DPP4DPP8DPP9 | |
| SCHEMBL31484012 | 0.79 | SLC6A3 (0.37) | DPP4DPP8DPP9 | |
| SCHEMBL31315955 | 0.79 | DPP4 (0.33) | DPP4DPP8DPP9PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319963-B1 | SUBSTITUTED 4-AZAINDOLES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-01-08 | — | — | EP | disclosed |