Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 16/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21613508 | 0.82 | EGLN1 (0.44) | EGLN1GRIN2BMAP4K4GRIN1 | |
| SCHEMBL23319270 | 0.82 | EGLN1 (0.46) | EGLN1GRIN2BMAP4K4GRIN1 | |
| SCHEMBL21613480 | 0.81 | EGLN1 (0.45) | EGLN1GRIN2BMAP4K4GRIN1 | |
| SCHEMBL21613470 | 0.77 | EGLN1 (0.44) | EGLN1GRIN2BMAP4K4GRIN1 | |
| SCHEMBL23319236 | 0.72 | EGLN1 (0.49) | EGLN1GRIN2BMAP4K4GRIN1 | |
| SCHEMBL21613439 | 0.72 | MAP4K4 (0.42) | EGLN1GRIN2BMAP4K4GRIN1 | |
| SCHEMBL21613598 | 0.71 | EGLN1 (0.42) | EGLN1GRIN2BMAP4K4GRIN1 | |
| SCHEMBL20049830 | 0.70 | EGLN1 (0.41) | EGLN1GRIN2BMAP4K4GRIN1 | |
| SCHEMBL25586500 | 0.70 | HSD17B10 (0.47) | EGLN1GRIN2BGRIN1 | |
| SCHEMBL20049894 | 0.69 | MAP4K4 (0.45) | EGLN1GRIN2BMAP4K4GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319963-B1 | SUBSTITUTED 4-AZAINDOLES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-01-08 | — | — | EP | disclosed |