Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | PPARG | P37231 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734727 | 0.88 | PPARG (0.74) | MAPTPPARGTP53MEN1KMT2A | |
| SCHEMBL2161521 | 0.86 | MAPT (0.55) | MAPTPPARGTP53POLB | |
| SCHEMBL12398304 | 0.84 | MAPT (0.72) | MAPTPPARGTP53POLB | |
| SCHEMBL14121323 | 0.84 | PPARG (0.63) | MAPTPPARGTP53 | |
| SCHEMBL2162601 | 0.83 | KDM4E (0.61) | MAPTPPARGTP53POLBMEN1 | |
| SCHEMBL14240990 | 0.80 | PPARG (0.68) | PPARG | |
| SCHEMBL14240991 | 0.80 | PPARG (0.66) | MAPTPPARGTP53 | |
| SCHEMBL14241281 | 0.80 | PPARG (0.68) | PPARG | |
| SCHEMBL2161526 | 0.80 | MEN1 (0.81) | MAPTTP53MEN1KMT2A | |
| SCHEMBL2162227 | 0.80 | MEN1 (0.74) | MAPTTP53POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985764-B2 | Amide derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20090062363-A1 | AMIDE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062363-A1 | AMIDE DERIVATIVE OR SALT THEREOF | HTR7, HTR2B, NPSR1 | MAPT 4469/4885PPARG 2441/4885TP53 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.