Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21615038 | 0.94 | PDK2 (0.36) | PDK2CDK1CDK2IRAK4 | |
| SCHEMBL25125137 | 0.91 | PDK2 (0.40) | PDK2CDK1CDK2IRAK4 | |
| SCHEMBL25124742 | 0.91 | PDK2 (0.37) | PDK2CDK1CDK2IRAK4 | |
| SCHEMBL25125075 | 0.87 | PDK2 (0.36) | PDK2 | |
| SCHEMBL22662287 | 0.86 | PDK2 (0.36) | PDK2 | |
| SCHEMBL19163603 | 0.85 | PDK2 (0.41) | PDK2 | |
| SCHEMBL29892124 | 0.85 | PDK2 (0.41) | PDK2 | |
| SCHEMBL796162 | 0.85 | PDK2 (0.43) | PDK2 | |
| SCHEMBL29440305 | 0.85 | PDK2 (0.43) | PDK2 | |
| SCHEMBL23136686 | 0.85 | PDK2 (0.44) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127251-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
| WO-2020007770-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MERCK PATENT GMBH (DE) | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127251-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MAOB, TYR, INMT | PDK2 805/4885JAK2 654/4885JAK3 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.