Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.61 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.61 |
| ▸ | TAF1 | P21675 | 1/20 | 0.61 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.61 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.61 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066767 | 0.76 | BRD4 (1.00) | BRD4BRD9TAF1BRPF1CREBBP | |
| SCHEMBL21615079 | 0.75 | BRD4 (0.40) | BRD4BRD9TAF1BRPF1CREBBP | |
| SCHEMBL24916388 | 0.73 | BRD4 (0.36) | BRD4BRD9TAF1BRPF1CREBBP | |
| SCHEMBL27037101 | 0.71 | CECR2 (0.61) | BRD4BRD9TAF1BRPF1CREBBP | |
| SCHEMBL28695187 | 0.70 | BRD4 (0.86) | BRD4BRD9TAF1BRPF1CREBBP | |
| SCHEMBL29062925 | 0.69 | BRD4 (0.41) | BRD4BRD9TAF1BRPF1CREBBP | |
| SCHEMBL24020756 | 0.69 | BRD4 (0.41) | BRD4BRD9TAF1BRPF1CREBBP | |
| SCHEMBL29063028 | 0.68 | BRD4 (0.41) | BRD4BRD9TAF1BRPF1CREBBP | |
| SCHEMBL6869444 | 0.67 | BRD4 (0.34) | BRD4BRD9 | |
| SCHEMBL29482204 | 0.67 | BRD9 (0.58) | BRD4BRD9TAF1BRPF1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020007322-A1 | COMPOUND TARGETED TO DEGRADE BET PROTEIN AND APPLICATION THEREOF | 清华大学 | 2020-01-09 | — | — | WO | disclosed |