Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937243 | 1.00 | FKBP1A (0.49) | FKBP1APOLBSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL4109077 | 0.94 | POLB (0.49) | FKBP1APOLBSMN1; SMN2TP53MMP2 | |
| SCHEMBL200913 | 0.94 | POLB (0.49) | FKBP1APOLBSMN1; SMN2TP53MMP2 | |
| SCHEMBL389987 | 0.94 | POLB (0.49) | FKBP1APOLBSMN1; SMN2TP53MMP2 | |
| Hydrochloric Acid SCHEMBL5159954 | 0.92 | POLB (0.47) | FKBP1APOLBSMN1; SMN2TP53MMP2 | |
| Hydrochloric Acid SCHEMBL3055388 | 0.92 | POLB (0.47) | FKBP1APOLBSMN1; SMN2TP53MMP2 | |
| Hydrochloric Acid SCHEMBL2337448 | 0.92 | POLB (0.47) | FKBP1APOLBSMN1; SMN2TP53MMP2 | |
| SCHEMBL2616299 | 0.80 | FKBP1A (0.49) | FKBP1APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL12886363 | 0.80 | FKBP1A (0.49) | FKBP1APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL15316989 | 0.80 | FKBP1A (0.49) | FKBP1APOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |