⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365472 | 0.96 | — | — | |
| SCHEMBL11015936 | 0.92 | — | — | |
| SCHEMBL28963958 | 0.92 | — | — | |
| SCHEMBL29120863 | 0.89 | — | — | |
| SCHEMBL29078422 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL23044765 | 0.78 | — | — | |
| SCHEMBL20236054 | 0.78 | — | — | |
| SCHEMBL3923932 | 0.78 | — | — | |
| SCHEMBL28650795 | 0.77 | — | — | |
| SCHEMBL10783167 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106631969-B | The synthetic method of carbazole and its derivative | 江汉大学 | 2019-06-07 | — | — | CN | claimed |
| CN-106631969-A | Synthetic method of carbazole and derivatives thereof | 江汉大学 | 2017-05-10 | — | — | CN | claimed |
| CN-117777107-A | CD73 inhibitory compounds and uses thereof | 华东理工大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-113061132-A | Condensed ring lactam compound, preparation method and application | 上海凌达生物医药有限公司 | 2021-07-02 | — | — | CN | disclosed |
| WO-2020011209-A1 | IMMUNOSUPPRESSIVE AGENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2020-01-16 | — | — | WO | disclosed |
| CN-105530932-B | Primary formamide as BTK inhibitor | 艾伯维公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-107001377-B | Pyrazolo [1,5-A] pyrimidine derivatives that there is the piperidines of inhibitory activity to replace the duplication of Respiratory Syncytial Virus(RSV) (RSV) | 爱尔兰詹森科学公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-107207512-B | Tricyclic pyrazole simultaneously [1, the 5-A] pyrimidine derivatives that there is the piperidines of inhibitory activity to replace the duplication of Respiratory Syncytial Virus(RSV) (RSV) | 爱尔兰詹森科学公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-110167930-A | ROR gamma modulators | 百时美施贵宝公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110114343-A | Pyrazolopyrimidine compound and its application method | 豪夫迈·罗氏有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-110036004-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 希洛斯医药品股份有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-103347882-A | Substituted N- (1H-indazol-4-yl) imidazo [1,2-a ] pyridine-3-carboxamide compounds as type III receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC | 2013-10-09 | — | — | CN | disclosed |
| CN-102822170-A | Substituted N-(1H-indazol-4-yl)imidazo[1, 2-a]pyridine-3- carboxamide compounds as cFMS inhibitors | ARRAY BIOPHARMA INC | 2012-12-12 | — | — | CN | disclosed |
| CN-102791710-A | 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine derivatives as CaMKII kinase inhibitors for treating cardiovascular diseases | SANOFI AVENTIS | 2012-11-21 | — | — | CN | disclosed |
| CN-102459216-A | Inhibitors of renal outer medullary potassium channels | MERCK SHARP & DO | 2012-05-16 | — | — | CN | disclosed |
| CN-102395558-A | Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy | ABBOTT GMBH & CO KG | 2012-03-28 | — | — | CN | disclosed |
| CN-102171188-A | Tripyridyl carboxamide orexin receptor antagonists | MERCK & CO INC | 2011-08-31 | — | — | CN | disclosed |
| CN-102159285-A | Macrocyclic quinoxaline compounds as hcv ns3 protease inhibitors | MERCK & CO INC | 2011-08-17 | — | — | CN | disclosed |
| CN-102089307-A | Pyrrolopyridines as kinase inhibitors | ARRAY BIOPHARMA INC | 2011-06-08 | — | — | CN | disclosed |
| CN-101400660-A | Triazole derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-04-01 | — | — | CN | disclosed |