Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.69 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23671499 | 0.85 | BACE1 (0.69) | BACE1LTA4HPTGS2 | |
| SCHEMBL23671503 | 0.82 | BACE1 (0.66) | BACE1LTA4HPTGS2HRH3 | |
| SCHEMBL21616860 | 0.82 | BACE1 (1.00) | BACE1HRH3 | |
| SCHEMBL23671491 | 0.81 | BACE1 (0.64) | BACE1 | |
| SCHEMBL23671494 | 0.80 | BACE1 (0.63) | BACE1LTA4HPTGS1PTGS2HRH3 | |
| SCHEMBL21622469 | 0.80 | BACE1 (1.00) | BACE1HRH3 | |
| SCHEMBL21616831 | 0.78 | BACE1 (0.77) | BACE1HRH3 | |
| SCHEMBL13946680 | 0.78 | LTA4H (0.55) | BACE1LTA4HPTGS1PTGS2HRH3 | |
| SCHEMBL4029263 | 0.78 | HTR2C (0.57) | BACE1LTA4HPTGS1PTGS2HRH3 | |
| SCHEMBL21616864 | 0.78 | BACE1 (1.00) | BACE1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230131-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) (FR) | 2021-07-29 | — | — | US | disclosed |
| EP-3820862-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-05-19 | — | — | EP | disclosed |
| WO-2020011848-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2020-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230131-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | ABCG2, SLC10A1, CYP3A43 | BACE1 1582/4885LTA4H 1469/4885PTGS1 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.