Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23928889 | 0.98 | ACACB (0.45) | ACACBEPHX2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL30587434 | 0.98 | ACACB (0.45) | ACACBEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL13339752 | 0.85 | ACACB (0.49) | ACACBEPHX2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL3493117 | 0.84 | ACACB (0.48) | ACACBEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL15469500 | 0.83 | EPHX2 (0.52) | ACACBEPHX2ADRA1DADRA1AADRA1B | |
| SCHEMBL1115206 | 0.81 | EPHX2 (0.50) | ACACBEPHX2ADRA1DADRA1AADRA1B | |
| SCHEMBL7299024 | 0.76 | ALDH1A1 (0.43) | ACACBEPHX2NPC1TDP2NSD2 | |
| SCHEMBL23928898 | 0.76 | EPHX2 (0.54) | ACACBEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL14919198 | 0.75 | EPHX2 (0.64) | ACACBEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL23957116 | 0.74 | ATM (0.55) | EPHX2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820869-B1 | SPIROCHROMANE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2023-08-30 | — | — | EP | claimed |
| EP-3820869-A1 | SPIROCHROMANE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2021-05-19 | — | — | EP | claimed |
| CN-112823157-A | Spirochroman derivatives | 吉瑞工厂 | 2021-05-18 | — | — | CN | claimed |
| WO-2020012422-A1 | SPIROCHROMANE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2020-01-16 | — | — | WO | claimed |
| EP-3820869-B1 | SPIROCHROMANE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2023-08-30 | — | — | EP | disclosed |