Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616424 | 0.88 | STING1 (0.41) | STING1ADORA2AMAPKAPK2HDAC1 | |
| SCHEMBL21616395 | 0.83 | STING1 (0.47) | STING1ADORA2A | |
| SCHEMBL21620360 | 0.82 | STING1 (0.42) | STING1ADORA2A | |
| Bromide SCHEMBL21616426 | 0.81 | STING1 (0.41) | STING1ADORA2A | |
| SCHEMBL21620379 | 0.79 | STING1 (0.64) | STING1 | |
| SCHEMBL21620363 | 0.79 | STING1 (0.39) | STING1ADORA2A | |
| SCHEMBL21630047 | 0.73 | KDM4E (0.41) | STING1ADORA2A | |
| SCHEMBL29689171 | 0.72 | STING1 (0.42) | STING1ADORA2A | |
| SCHEMBL28752005 | 0.72 | STING1 (0.42) | STING1ADORA2A | |
| SCHEMBL28752004 | 0.72 | STING1 (0.42) | STING1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020010451-A1 | HETEROAROMATIC-FUSED IMIDAZOLYL AMIDES, COMPOSITIONS AND USES THEREOF AS STING AGONISTS | TRILLIUM THERAPEUTICS INC. (CA) | 2020-01-16 | — | — | WO | disclosed |