Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620360 | 0.89 | STING1 (0.42) | STING1ADORA2AHPGDS | |
| Bromide SCHEMBL21616426 | 0.88 | STING1 (0.41) | STING1ADORA2AHPGDS | |
| SCHEMBL27207460 | 0.87 | STING1 (0.41) | STING1ADORA2A | |
| SCHEMBL27204002 | 0.87 | STING1 (0.41) | STING1ADORA2A | |
| SCHEMBL21616395 | 0.81 | STING1 (0.47) | STING1ADORA2A | |
| SCHEMBL28752005 | 0.79 | STING1 (0.42) | STING1ADORA2A | |
| SCHEMBL29689171 | 0.79 | STING1 (0.42) | STING1ADORA2A | |
| SCHEMBL28752004 | 0.79 | STING1 (0.42) | STING1ADORA2A | |
| SCHEMBL21620380 | 0.79 | DRD3 (0.39) | STING1ADORA2A | |
| SCHEMBL21616424 | 0.78 | STING1 (0.41) | STING1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020010451-A1 | HETEROAROMATIC-FUSED IMIDAZOLYL AMIDES, COMPOSITIONS AND USES THEREOF AS STING AGONISTS | TRILLIUM THERAPEUTICS INC. (CA) | 2020-01-16 | — | — | WO | disclosed |