Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.52 |
| ▸ | HRH2 | P25021 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621022 | 0.84 | KDM4E (0.64) | HRH3HRH2HRH1HTR1AHTR7 | |
| SCHEMBL30395141 | 0.81 | KDM4E (0.60) | MEN1KMT2AHRH3HRH2HRH1 | |
| SCHEMBL19897903 | 0.81 | KDM4E (0.60) | MEN1KMT2AHRH3HRH2HRH1 | |
| SCHEMBL30272050 | 0.81 | KDM4E (0.60) | MEN1KMT2AHRH3HRH2HRH1 | |
| SCHEMBL19897905 | 0.81 | KDM4E (0.60) | MEN1KMT2AHRH3HRH2HRH1 | |
| SCHEMBL24302740 | 0.81 | HRH3 (0.52) | HRH3HRH2HRH1HTR1AHTR7 | |
| SCHEMBL5544810 | 0.81 | LTA4H (0.69) | HRH3HRH2HRH1LTA4HKDM4E | |
| SCHEMBL21620996 | 0.81 | KDM4E (0.59) | MEN1KMT2AHRH3HRH2HRH1 | |
| SCHEMBL8265599 | 0.80 | KDM4E (0.55) | HRH3HRH2HRH1HTR1ALTA4H | |
| SCHEMBL12015747 | 0.80 | HRH3 (0.64) | MEN1KMT2AHRH3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011243-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-01-16 | — | — | WO | disclosed |