Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161720 | 0.93 | KMT2A (0.88) | MEN1KMT2ATDP1 | |
| SCHEMBL2161604 | 0.91 | KMT2A (1.00) | MEN1KMT2ATDP1MAPTTP53 | |
| SCHEMBL2161493 | 0.91 | KMT2A (0.80) | MEN1KMT2ATDP1MAPTTP53 | |
| SCHEMBL2161422 | 0.88 | MEN1 (0.72) | MEN1KMT2ATDP1MAPTTP53 | |
| SCHEMBL2162259 | 0.87 | MEN1 (0.73) | MEN1KMT2AMAPTTP53 | |
| SCHEMBL2161690 | 0.87 | MEN1 (0.71) | MEN1KMT2AMAPTTP53 | |
| SCHEMBL2161438 | 0.87 | MAPT (0.79) | MEN1KMT2AMAPTTP53 | |
| SCHEMBL2161500 | 0.86 | MEN1 (0.86) | MEN1KMT2A | |
| SCHEMBL2162139 | 0.86 | MEN1 (0.69) | MEN1KMT2AMAPTTP53 | |
| SCHEMBL11981687 | 0.85 | MEN1 (0.69) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384550-A | Amide derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-11 | — | — | CN | claimed |
| US-20090062363-A1 | AMIDE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-03-05 | — | — | US | claimed |
| EP-1988076-A1 | AMIDE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-05 | — | — | EP | claimed |
| CN-101384550-B | Amide derivative or salt thereof | ASTELLAS PHARMA INC | 2011-08-31 | — | — | CN | disclosed |
| US-7985764-B2 | Amide derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-07-26 | — | — | US | disclosed |
| CN-101384550-A | Amide derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-11 | — | — | CN | disclosed |
| US-20090062363-A1 | AMIDE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1988076-A1 | AMIDE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062363-A1 | AMIDE DERIVATIVE OR SALT THEREOF | HTR7, HTR2B, NPSR1 | MEN1 3828/4885KMT2A 2331/4885TDP1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.