SCHEMBL21622154

SCHEMBL21622154

O=S1(=O)CCCC1CCCCCCN=C=S

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 4/20 0.38
NFE2L2 Q16236 4/20 0.38
MIF P14174 3/20 0.38
NAAA Q02083 2/20 0.38
GSK3B P49841 1/20 0.37
TRPA1 O75762 7/20 0.35
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
BACH1 O14867 1/20 0.34
MAFK O60675 1/20 0.34
EGFR P00533 1/20 0.34
PTGS2 P35354 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21622157 0.95 KEAP1 (0.40) KEAP1NFE2L2MIFNAAAGSK3B
SCHEMBL7711924 0.73 EPHX1 (0.38) NAAAALDH1A1LMNA
SCHEMBL14976126 0.73 EPHX1 (0.38) NAAAALDH1A1LMNA
SCHEMBL10773640 0.73 EPHX1 (0.38) NAAAALDH1A1LMNA
SCHEMBL10620419 0.73 EPHX1 (0.38) NAAAALDH1A1LMNA
SCHEMBL1911580 0.71 EPHX1 (0.35) NAAAALDH1A1LMNA
SCHEMBL11705481 0.71 EPHX1 (0.35) NAAAALDH1A1LMNA
SCHEMBL14153027 0.71 EPHX1 (0.35) NAAAALDH1A1LMNA
SCHEMBL18937148 0.69 CYP1A2 (0.40)
SCHEMBL1419553 0.69 CYP1A2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020011750-A1 FUNGICIDES TO PREVENT AND CONTROL FUNGAL PATHOGENS Université de Lausanne (CH) 2020-01-16 WO disclosed