Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29650434 | 0.81 | CCR1 (0.62) | MAPTCYP3A4LMNAPMP22MAPK1 | |
| SCHEMBL10506533 | 0.81 | CCR1 (0.62) | MAPTCYP3A4LMNAPMP22MAPK1 | |
| SCHEMBL2206337 | 0.79 | CCR1 (0.50) | MAPTLMNAMAPK1ALDH1A1KDM4E | |
| SCHEMBL30913269 | 0.77 | NR4A2 (0.55) | MAPTCYP3A4LMNAPMP22APEX1 | |
| SCHEMBL22117517 | 0.77 | KDM4E (0.58) | MAPTCYP3A4LMNAPMP22MAPK1 | |
| SCHEMBL23487729 | 0.77 | MAPT (0.46) | MAPTCYP3A4LMNAPMP22APEX1 | |
| SCHEMBL11473713 | 0.77 | CCR1 (0.68) | MAPTCYP3A4LMNAPMP22APEX1 | |
| SCHEMBL8602672 | 0.77 | CYP1A2 (0.48) | MAPTCYP3A4LMNAPMP22APEX1 | |
| SCHEMBL29720527 | 0.77 | CCR1 (0.68) | MAPTCYP3A4LMNAPMP22APEX1 | |
| SCHEMBL3194625 | 0.75 | LMNA (0.55) | MAPTCYP3A4LMNAPMP22APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820965-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |
| WO-2020011658-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-01-16 | — | — | WO | disclosed |