Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917373 | 0.72 | MAPK14 (0.37) | MAPK8MAPK10MAPK14ACVRL1MAPT | |
| SCHEMBL3475625 | 0.64 | MAPK14 (0.54) | MAPK8MAPK10MAPK14ACVRL1MAPT | |
| SCHEMBL6354557 | 0.61 | MAPK14 (0.49) | MAPK8MAPK10MAPK14ACVRL1MAPT | |
| SCHEMBL30902223 | 0.60 | TDP1 (0.61) | MAPK8MAPK10MAPK14MAPTAURKA | |
| SCHEMBL3279472 | 0.60 | TDP1 (0.61) | MAPK8MAPK10MAPK14MAPTAURKA | |
| Hydrochloric Acid SCHEMBL6370463 | 0.58 | MAPK10 (0.97) | MAPK8MAPK10MAPK14MAPT | |
| SCHEMBL28709843 | 0.57 | MEN1 (0.55) | MAPK8MAPK10MAPK14MAPTTSHR | |
| SCHEMBL6355590 | 0.57 | MAPK14 (0.47) | MAPK8MAPK10MAPK14ACVRL1MAPT | |
| SCHEMBL3225644 | 0.57 | CYP3A4 (0.60) | MAPK14MAPTTSHR | |
| SCHEMBL28976313 | 0.57 | GSK3B (0.51) | MAPK8MAPK10MAPK14ACVRL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820966-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-08 | — | — | EP | disclosed |
| WO-2020011686-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-01-16 | — | — | WO | disclosed |