Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | FADS1 | O60427 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622875 | 0.72 | MAPK8 (0.41) | MAPK14MAPK8MAPK10ACVRL1TSHR | |
| SCHEMBL1670886 | 0.70 | NOS1 (0.33) | — | |
| SCHEMBL29383163 | 0.70 | NOS1 (0.33) | — | |
| SCHEMBL16914935 | 0.64 | MAPK14 (0.36) | MAPK14MAPK8MAPK10ACVRL1TSHR | |
| SCHEMBL6354557 | 0.64 | MAPK14 (0.49) | MAPK14MAPK8MAPK10ACVRL1TSHR | |
| SCHEMBL13232841 | 0.60 | TSHR (0.46) | MAPK14MAPK8MAPK10ACVRL1TSHR | |
| SCHEMBL6355590 | 0.60 | MAPK14 (0.47) | MAPK14MAPK8MAPK10ACVRL1TSHR | |
| SCHEMBL28976313 | 0.60 | GSK3B (0.51) | MAPK14MAPK8MAPK10ACVRL1TSHR | |
| SCHEMBL11175497 | 0.60 | GAA (0.49) | MAPK14MAPK8MAPK10TSHRKMT2A | |
| SCHEMBL30902223 | 0.59 | TDP1 (0.61) | MAPK14MAPK8MAPK10TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | MAPK14 3582/4885MAPK8 3589/4885MAPK10 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.