Tyrosine

Tyrosine

SCHEMBL2162292

N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C1NC(=S)NC1c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.55
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
HDAC8 Q9BY41 2/20 0.42
GUSB P08236 2/20 0.41
ALDH1A1 P00352 1/20 0.41
OPRM1 P35372 5/20 0.40
OPRD1 P41143 5/20 0.40
OPRK1 P41145 1/20 0.40
DHFR P00374 1/20 0.40
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL18222727 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL28900255 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL28244030 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL27641183 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL5699043 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL133206 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL5699039 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL1908049 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL1908048 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL1003558 0.75 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338153-B2 Recombinant hexose oxidase, a method of producing same and use of such enzyme DUPONT NUTRITION BIOSCIENCES APS (DK) 2012-12-25 US disclosed
US-8178090-B2 Recombinant hexose oxidase DANISCO A/S (DK) 2012-05-15 US disclosed
US-20110183037-A1 Recombinant hexose oxidase, a method of producing same and use of such enzyme DANISCO A/S (DK) 2011-07-28 US disclosed
US-7745599-B1 Hexose oxidase-encoding DNAs and methods of use thereof DANISCO A/S (DK) 2010-06-29 US disclosed
US-7727572-B2 Recombinant hexose oxidase, a method of producing same and use of such enzyme DANISCO A/S (DK) 2010-06-01 US disclosed
US-20090275103-A1 Recombinant hexose oxidase DANISCO A/S (DK) 2009-11-05 US disclosed
US-7544795-B2 Recombinant hexose oxidase, a method of producing same and use of such enzyme DANISCO A/S (DK) 2009-06-09 US disclosed
US-20090041899-A1 Recombinant hexose oxidase, a method of producing same and use of such enzyme DANISCO A/S (DK) 2009-02-12 US disclosed
EP-0832245-B2 RECOMBINANT HEXOSE OXIDASE, A METHOD OF PRODUCING SAME AND USE OF SUCH ENZYME DANISCO (DK) 2008-09-10 EP disclosed
CN-1266275-C Recombinant hexose oxidase, a method of producing same and use of such enzyme BIOTEKNOLOGISK INST (DK) 2006-07-26 CN disclosed
US-20050282249-A1 Recombinant hexose oxidase, a method of producing same and use of such enzyme DUPONT NUTRITION BIOSCIENCES APS (DK) 2005-12-22 US disclosed
US-6924366-B2 Recombinant hexose oxidase, a method of producing same and use of such enzyme BIOTEKNOLOGISK INSTITUT (DK) 2005-08-02 US disclosed
EP-0832245-B1 RECOMBINANT HEXOSE OXIDASE, A METHOD OF PRODUCING SAME AND USE OF SUCH ENZYME DANISCO (DK) 2002-09-04 EP disclosed
US-20020106725-A1 Recombinant hexose oxidase, a method of producing same and use of such enzyme BIOTEKNOLOGISK INSTITUT 2002-08-08 US disclosed
US-6251626-B1 GENERATING ENZYMATIC POLYPEPTIDE; INSERT EXPRESSION VECTOR INTO CELL, CULTURE CELLS, RECOVER ENZYMATIC POLYPEPTIDE BIOTEKNOLOGISK INSTITUT (DK) 2001-06-26 US disclosed
EP-1020523-A2 Recombinant hexose oxidase, a method of producing same and use of such enzyme Bioteknologisk Institut (DK) 2000-07-19 EP disclosed
EP-0832245-A1 RECOMBINANT HEXOSE OXIDASE, A METHOD OF PRODUCING SAME AND USE OF SUCH ENZYME BIOTEKNOLOGISK INSTITUT (DK) 1998-04-01 EP disclosed
WO-1996040935-A1 RECOMBINANT HEXOSE OXIDASE, A METHOD OF PRODUCING SAME AND USE OF SUCH ENZYME BIOTEKNOLOGISK INSTITUT (DK) 1996-12-19 WO disclosed