Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.60 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.60 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622945 | 0.87 | CD274 (0.53) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21623099 | 0.85 | CD274 (0.42) | CD274PDCD1 | |
| SCHEMBL21623002 | 0.82 | CD274 (0.73) | CD274PDCD1 | |
| SCHEMBL21623003 | 0.81 | CD274 (0.64) | CD274PDCD1 | |
| SCHEMBL28478270 | 0.80 | CD274 (0.63) | CD274PDCD1 | |
| SCHEMBL21616720 | 0.79 | CD274 (0.38) | CD274PDCD1 | |
| SCHEMBL30341054 | 0.79 | CD274 (0.38) | CD274PDCD1 | |
| SCHEMBL21616723 | 0.79 | CD274 (0.38) | CD274PDCD1 | |
| SCHEMBL21622944 | 0.78 | ERN1 (0.39) | CD274PDCD1 | |
| SCHEMBL21623091 | 0.76 | PDCD1 (0.37) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011209-A1 | IMMUNOSUPPRESSIVE AGENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2020-01-16 | — | — | WO | disclosed |