Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.53 |
| ▸ | PDCD1 | Q15116 | 13/20 | 0.53 |
| ▸ | PDCD1LG2 | Q9BQ51 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622946 | 0.87 | CD274 (0.60) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21622992 | 0.85 | PDCD1 (0.75) | CD274PDCD1 | |
| SCHEMBL21623041 | 0.84 | CD274 (0.66) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21622896 | 0.83 | PDCD1 (0.61) | CD274PDCD1 | |
| SCHEMBL21623013 | 0.83 | PDCD1 (0.67) | CD274PDCD1 | |
| SCHEMBL28473503 | 0.82 | CD274 (0.46) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21623121 | 0.82 | CD274 (0.46) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL26555409 | 0.81 | CD274 (0.56) | CD274PDCD1 | |
| SCHEMBL28469670 | 0.81 | CD274 (0.48) | CD274PDCD1 | |
| SCHEMBL30340342 | 0.81 | PDCD1 (0.50) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011209-A1 | IMMUNOSUPPRESSIVE AGENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2020-01-16 | — | — | WO | disclosed |