⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203984 | 1.00 | — | — | |
| SCHEMBL11273675 | 0.78 | — | — | |
| SCHEMBL28760995 | 0.75 | — | — | |
| SCHEMBL477867 | 0.73 | — | — | |
| SCHEMBL10125 | 0.73 | — | — | |
| SCHEMBL477908 | 0.73 | — | — | |
| Halothane SCHEMBL28249845 | 0.72 | ALDH1A1 (0.79) | — | |
| SCHEMBL8899596 | 0.70 | — | — | |
| SCHEMBL23164 | 0.70 | — | — | |
| SCHEMBL15638641 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747222-A1 | PROCESSES TO PRODUCE HFO-1252ZC FROM HCFO-1233XF AND HBFO-1233XFB | The Chemours Company FC, LLC (US) | 2026-05-27 | — | — | EP | claimed |
| WO-2025019193-A1 | PROCESSES TO PRODUCE HFO-1252ZC FROM HCFO-1233XF AND HBFO-1233XFB | THE CHEMOURS COMPANY FC, LLC (US) | 2025-01-23 | — | — | WO | claimed |
| CN-111393389-A | Method for synthesizing 3- (trifluoromethyl) azetidinone by palladium catalysis | 西安工程大学 | 2020-07-10 | — | — | CN | claimed |
| CN-109369354-A | A kind of synthetic method of tri- fluoro butanol of 4,4,4- | 浦拉司科技（上海）有限责任公司 | 2019-02-22 | — | — | CN | claimed |
| CN-108101739-A | The continuous method for preparing tri- fluoro- 1,2- propylene glycol of 3,3,3- | 西安近代化学研究所 | 2018-06-01 | — | — | CN | claimed |
| CN-102964207-A | Preparation method of 2-bromo-3,3,3-trifluoropropene | WEIHAI NEWERA CHEMICAL CO LTD | 2013-03-13 | — | — | CN | claimed |
| EP-1119534-B1 | METHOD FOR THE PREPARATION OF 3-BROMO-1,1,1-TRIFLUOROPROPANE | GREAT LAKES CHEMICAL CORP (US) | 2004-03-03 | — | — | EP | claimed |
| EP-4747222-A1 | PROCESSES TO PRODUCE HFO-1252ZC FROM HCFO-1233XF AND HBFO-1233XFB | The Chemours Company FC, LLC (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-4747222-A1 | PROCESSES TO PRODUCE HFO-1252ZC FROM HCFO-1233XF AND HBFO-1233XFB | The Chemours Company FC, LLC (US) | 2026-05-27 | — | — | EP | disclosed |
| CN-115925509-B | Preparation method of 3, 3-trifluoropropene | 山东华安新材料有限公司 | 2025-02-18 | — | — | CN | disclosed |
| WO-2025019193-A1 | PROCESSES TO PRODUCE HFO-1252ZC FROM HCFO-1233XF AND HBFO-1233XFB | THE CHEMOURS COMPANY FC, LLC (US) | 2025-01-23 | — | — | WO | disclosed |
| WO-2025019193-A1 | PROCESSES TO PRODUCE HFO-1252ZC FROM HCFO-1233XF AND HBFO-1233XFB | THE CHEMOURS COMPANY FC, LLC (US) | 2025-01-23 | — | — | WO | disclosed |
| CN-115260186-B | VMAT2 inhibitor and preparation method and application thereof | 山东绿叶制药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-1263084-A | 1-trifluoromethyl-2-alkylvinylaniline derivative and its synthesis | SHANGHAI INST ORGANIC CHEM (CN) | 2000-08-16 | — | — | CN | disclosed |
| WO-2000020362-A1 | METHOD FOR THE PREPARATION OF 3-BROMO-1,1,1-TRIFLUOROPROPANE | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-04-13 | — | — | WO | disclosed |
| US-5962754-A | CATALYTIC BROMINATION OF 3,3,,3-TRIFLUOROPROPENE | GREAT LAKES CHEMICAL CORPORATION (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0425622-B1 | MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 1994-10-12 | — | — | EP | disclosed |
| US-5308537-A | Unsaturated liquid crystal compounds containing trifluoromethyl groups | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-05-03 | — | — | US | disclosed |
| EP-0425622-A1 | MESOGENIC COMPOUNDS. | MERCK PATENT GMBH (DE) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990013610-A1 | MESOGENIC COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-11-15 | — | — | WO | disclosed |