Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 12/20 | 1.00 |
| ▸ | ICAM1 | P05362 | 12/20 | 1.00 |
| ▸ | ITGAL | P20701 | 12/20 | 1.00 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.71 |
| ▸ | ACE | P12821 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21623656 | 1.00 | ITGB2 (1.00) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL11874268 | 0.90 | ITGB2 (0.81) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL23092632 | 0.90 | ITGB2 (0.81) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL9466705 | 0.88 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL5259129 | 0.88 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL30616778 | 0.88 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL5191302 | 0.88 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL22206878 | 0.87 | ITGB2 (0.77) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL22206876 | 0.87 | ITGB2 (0.77) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL7402984 | 0.86 | ITGB2 (0.76) | ITGB2ICAM1ITGALERAP2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014726-A1 | TREATMENT FOR LIVER REGENERATION | XENEXUS PHARMACEUTICALS PTY. LTD. (AU) | 2020-01-23 | — | — | WO | disclosed |