Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 9/20 | 0.78 |
| ▸ | ICAM1 | P05362 | 9/20 | 0.78 |
| ▸ | ITGAL | P20701 | 9/20 | 0.78 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.77 |
| ▸ | CTSL | P07711 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | ACE | P12821 | 2/20 | 0.68 |
| ▸ | TACR1 | P25103 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616778 | 1.00 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL5191302 | 1.00 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL5259129 | 1.00 | ITGB2 (0.78) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL22206878 | 0.99 | ITGB2 (0.77) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL22206876 | 0.99 | ITGB2 (0.77) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL11870861 | 0.94 | ERAP2 (0.76) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL9828348 | 0.93 | ERAP2 (0.74) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL9828342 | 0.93 | ERAP2 (0.74) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL23092632 | 0.92 | ITGB2 (0.81) | ITGB2ICAM1ITGALERAP2CTSL | |
| SCHEMBL21623652 | 0.92 | ERAP2 (0.72) | ITGB2ICAM1ITGALERAP2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219731-A | Cleaving an oxazolone precursor with lipase | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-06-15 | — | — | US | disclosed |