Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 1.00 |
| ▸ | FAAH | O00519 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420045 | 0.81 | FAAH (0.68) | MGLLFAAHCYP3A4HDAC3HDAC1 | |
| SCHEMBL2209404 | 0.78 | FAAH (0.64) | MGLLFAAHCYP3A4HDAC3HDAC1 | |
| SCHEMBL2208695 | 0.78 | FAAH (0.64) | MGLLFAAHCYP3A4HDAC3HDAC1 | |
| Phenylbutanoic Acid SCHEMBL20610729 | 0.77 | CYP3A4 (0.70) | MGLLFAAHCYP3A4HDAC3HDAC1 | |
| SCHEMBL2206712 | 0.77 | FAAH (0.62) | MGLLFAAHCYP3A4HDAC3HDAC1 | |
| SCHEMBL12414100 | 0.76 | FAAH (0.61) | MGLLFAAHCYP3A4HDAC3HDAC1 | |
| SCHEMBL29374812 | 0.76 | FAAH (0.61) | MGLLFAAHCYP3A4HDAC3HDAC1 | |
| SCHEMBL17084609 | 0.76 | HDAC1 (0.70) | MGLLFAAHCYP3A4HDAC3HDAC1 | |
| SCHEMBL8754823 | 0.76 | CYP3A4 (0.71) | MGLLFAAHCYP3A4 | |
| SCHEMBL29720556 | 0.76 | FAAH (0.61) | MGLLFAAHCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3823610-A1 | METHODS OF TREATING RENAL DISEASE | The Regents of the University of California (US) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020018554-A1 | METHODS OF TREATING RENAL DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-01-23 | — | — | WO | disclosed |