Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193916 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1792016 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL250009 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| Water SCHEMBL8817645 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28763213 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28873134 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL1718427 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21788097 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20670455 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21763039 | 0.78 | TAAR1 (0.48) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3823745-A1 | STIMULI-RESPONSIVE MICRO-RESERVOIRS FOR RELEASE OF ENCAPSULANTS | SAS Nanotechnologies LLC (US) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020018555-A1 | STIMULI-RESPONSIVE MICRO-RESERVOIRS FOR RELEASE OF ENCAPSULANTS | SAS Nanotechnologies LLC (US) | 2020-01-23 | — | — | WO | disclosed |
| US-9394540-B2 | Modified iRNA agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-07-19 | — | — | US | disclosed |