Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023659 | 0.76 | PLCG1 (0.60) | KMT2ATDP1RECQLEPHX2CA2 | |
| SCHEMBL30896659 | 0.71 | KEAP1 (0.44) | KMT2ATDP1SOAT1EPHX2KEAP1 | |
| SCHEMBL1911906 | 0.70 | KEAP1 (0.58) | KMT2ATDP1RECQLEPHX2PSIP1 | |
| SCHEMBL4629452 | 0.70 | CA1 (0.50) | KMT2ATDP1CA2KEAP1NFE2L2 | |
| SCHEMBL15915533 | 0.70 | PLCG1 (0.61) | KMT2ATDP1RECQLALOX5APFEN1 | |
| SCHEMBL2061849 | 0.70 | ALOX5AP (0.43) | KMT2ATDP1ALOX5APFEN1KAT6A | |
| SCHEMBL3665317 | 0.70 | RECQL (0.49) | RECQLALOX5APFEN1SOAT1EPHX2 | |
| SCHEMBL2163747 | 0.70 | EDNRB (0.36) | KMT2ATDP1KAT6ACA2PLCG1 | |
| SCHEMBL776476 | 0.70 | PTGES2 (0.44) | KMT2ATDP1ALOX5APFEN1KAT6A | |
| SCHEMBL6871921 | 0.70 | EDNRB (0.36) | KMT2ATDP1KAT6ACA2PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020020308-A1 | BRD4 INHIBITOR, PREPARATION METHOD AND USE THEREOF | 成都海创药业有限公司 | 2020-01-30 | — | — | WO | disclosed |