SCHEMBL2163379

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2163132	0.80	ALK (0.47)	ALKNPM1ALDH1A1MAPTLCK
	SCHEMBL2163926	0.79	ALK (0.49)	ALKNPM1ALDH1A1RAB9ASMN1; SMN2
	SCHEMBL2162634	0.78	NPM1 (0.47)	ALKNPM1ALDH1A1RAB9ASMN1; SMN2
	SCHEMBL2163015	0.77	ALK (0.46)	ALKNPM1ALDH1A1RAB9ASMN1; SMN2
	SCHEMBL2164020	0.75	ALK (0.45)	ALKNPM1KMT2ALCKFLT3
	SCHEMBL2163052	0.74	ALK (0.41)	ALKNPM1ALDH1A1KDM4EMEN1
	SCHEMBL12324172	0.73	ALK (0.59)	ALKNPM1ALDH1A1RAB9ASMN1; SMN2
	SCHEMBL2162897	0.71	ALDH1A1 (0.52)	ALKNPM1ALDH1A1RAB9ASMN1; SMN2
	SCHEMBL2163296	0.70	ALK (0.60)	ALKNPM1ALDH1A1RAB9ASMN1; SMN2
	SCHEMBL12323543	0.69	CYP17A1 (0.44)	ALKALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.