Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14691754 | 0.78 | TSHR (0.39) | TSHR | |
| SCHEMBL31020205 | 0.77 | TSHR (0.37) | TSHR | |
| SCHEMBL25487726 | 0.75 | TSHR (0.41) | TSHR | |
| SCHEMBL14691755 | 0.73 | TSHR (0.34) | TSHR | |
| SCHEMBL16699656 | 0.73 | TSHR (0.34) | TSHR | |
| SCHEMBL16369861 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL16700527 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL7258527 | 0.67 | TSHR (0.40) | TSHR | |
| SCHEMBL30685957 | 0.67 | TSHR (0.36) | TSHR | |
| SCHEMBL21633620 | 0.66 | PKM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3829570-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTA[C]PYRROLES, SUBSTITUTED DIHYDROPYRROLIZINES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020023710-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTA[C]PYRROLES, SUBSTITUTED DIHYDROPYRROLIZINES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-01-30 | — | — | WO | disclosed |