⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320888 | 0.80 | — | — | |
| SCHEMBL29825094 | 0.75 | — | — | |
| SCHEMBL1578686 | 0.75 | — | — | |
| SCHEMBL1764662 | 0.75 | — | — | |
| SCHEMBL8059308 | 0.75 | — | — | |
| SCHEMBL165155 | 0.72 | — | — | |
| SCHEMBL1331827 | 0.72 | — | — | |
| SCHEMBL109417 | 0.72 | — | — | |
| SCHEMBL337725 | 0.72 | — | — | |
| Hexachloroethane SCHEMBL9440057 | 0.71 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030880-B2 | Iminosulfanone compound as bromodomain protein inhibitor and pharmaceutical composition and medical use thereof | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-07-09 | — | — | US | disclosed |
| CN-115716827-A | Iminosulfones compound as bromodomain protein inhibitor, pharmaceutical composition and medical application thereof | 正大天晴药业集团股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-112424200-B | Iminosulfones compound as bromodomain protein inhibitor, pharmaceutical composition and medical application thereof | 正大天晴药业集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| US-20210300923-A1 | SULFOXIMINE COMPOUND AS BROMODOMAIN PROTEIN INHIBITOR AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-09-30 | — | — | US | disclosed |
| EP-3828183-A1 | SULFOXIMINE COMPOUND AS BROMODOMAIN PROTEIN INHIBITOR AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-06-02 | — | — | EP | disclosed |
| CN-112424200-A | Iminosulfones compound as bromodomain protein inhibitor, pharmaceutical composition and medical application thereof | 正大天晴药业集团股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| WO-2020020288-A1 | SULFOXIMINE COMPOUND AS BROMODOMAIN PROTEIN INHIBITOR AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 正大天晴药业集团股份有限公司 | 2020-01-30 | — | — | WO | disclosed |
| CN-1182953-C | Process for making moldable thermoplastic polymer foams and foams made thereby | A | 2005-01-05 | — | — | CN | disclosed |
| CN-1068353-C | moldable thermoplastic polymer beads | DENNIS A KNAUS (US) | 2001-07-11 | — | — | CN | disclosed |
| CN-1298790-A | Process for making moldable thermoplastic polymer foams and foams made thereby | DANIS A KNOTH (US) | 2001-06-13 | — | — | CN | disclosed |
| CN-1160411-A | moldable thermoplastic polymer beads | DENNIS A KNAUS (US) | 1997-09-24 | — | — | CN | disclosed |