Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704015 | 0.94 | NR3C2 (0.43) | NR3C2ESR1ESR2ALDH1A1CYP3A4 | |
| SCHEMBL22636511 | 0.87 | ESR1 (0.50) | NR3C2ESR1ESR2ALDH1A1CYP3A4 | |
| SCHEMBL998287 | 0.87 | ESR1 (0.50) | NR3C2ESR1ESR2ALDH1A1CYP3A4 | |
| SCHEMBL22636537 | 0.84 | ESR1 (0.52) | ESR1ESR2ALDH1A1CYP3A4ALOX12 | |
| SCHEMBL998286 | 0.81 | ESR1 (0.50) | ESR1ESR2ALDH1A1CYP3A4ALOX12 | |
| SCHEMBL1704016 | 0.79 | ESR1 (0.46) | ESR1ESR2ALDH1A1CYP3A4ALOX12 | |
| SCHEMBL158574 | 0.79 | NR3C2 (0.60) | NR3C2ESR1ESR2ALDH1A1CYP3A4 | |
| SCHEMBL14136110 | 0.78 | NR3C2 (0.49) | NR3C2ESR1ESR2ALDH1A1CYP3A4 | |
| SCHEMBL18715948 | 0.78 | ALDH1A1 (0.44) | NR3C2ESR1ESR2ALDH1A1CYP3A4 | |
| SCHEMBL21634388 | 0.77 | NR3C2 (0.50) | NR3C2ESR1ESR2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3830233-A1 | STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS | Milliken & Company (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020023897-A1 | STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS | MILLIKEN & COMPANY (US) | 2020-01-30 | — | — | WO | disclosed |