Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997283 | 1.00 | CTSC (0.44) | CTSCTSHRANPEPERAP1TDP1 | |
| SCHEMBL4323888 | 1.00 | CTSC (0.44) | CTSCTSHRANPEPERAP1TDP1 | |
| SCHEMBL8688252 | 0.89 | GAA (0.46) | CTSCTDP1 | |
| SCHEMBL8688302 | 0.89 | GAA (0.46) | CTSCTDP1 | |
| SCHEMBL8690046 | 0.89 | GAA (0.46) | CTSCTDP1 | |
| SCHEMBL8008396 | 0.88 | FAAH (0.44) | TSHRTDP1SLC6A3FAAH | |
| SCHEMBL12570603 | 0.86 | FAAH (0.50) | SLC6A3FAAH | |
| SCHEMBL864174 | 0.85 | FAAH (0.52) | FAAH | |
| SCHEMBL11807544 | 0.85 | FAAH (0.52) | FAAH | |
| SCHEMBL18240095 | 0.85 | FAAH (0.52) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048346-A1 | Synthesis of chiral intermediates useful in preparing pharmacologically active compounds | FERMENTA BIOTECH LTD. (IN) | 2004-03-11 | — | — | US | claimed |
| EP-1335988-A2 | SYNTHESIS OF CHIRAL INTERMEDIATES USEFUL IN PREPARING PHARMACOLOGICALLY ACTIVE COMPOUNDS | Fermenta Biotech Ltd (IN) | 2003-08-20 | — | — | EP | claimed |
| WO-2002042244-A2 | SYNTHESIS OF CHIRAL INTERMEDIATES USEFUL IN PREPARING PHARMACOLOGICALLY ACTIVE COMPOUNDS | FERMENTA BIOTECH LTD (GB) | 2002-05-30 | — | — | WO | claimed |
| EP-0610049-B1 | Process for producing optically active alpha-hydroxycarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-11-03 | — | — | EP | claimed |
| EP-0610048-B1 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-09-22 | — | — | EP | claimed |
| US-5714357-A | Process for producing optically active α-hydroxycarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-02-03 | — | — | US | claimed |
| US-5580765-A | A CULTURE PRODUCT OF A-HYDROXYNITRILE OR A MIXTURE OF ALDEHYDE AND PRUSSIC ACID | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0610048-A2 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | claimed |
| EP-0610049-A2 | Process for producing optically active alpha-hydroxycarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | claimed |
| CN-119192025-A | Industrial preparation method and application of alpha-hydroxynitrile | 哈尔滨理工大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-113866321-B | Detection method of body-building and digestion-promoting liquid | 云南省食品药品监督检验研究院 | 2024-11-22 | — | — | CN | disclosed |
| EP-4001422-A1 | PREPARATION OF OPTICALLY ACTIVE CYANOHYDRINS FROM ALDEHYDES AND KETONES USING A BIPHASIC HYDROXYNITRILE LYASE-CATALYZED HYDROCYANATION PROCESS | Enzymaster Deutschland GmbH (DE) | 2022-05-25 | — | — | EP | disclosed |
| CN-113584096-A | Preparation method and application of R-2-hydroxybenzene butyronitrile | 江西科苑生物股份有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-106520743-B | Recombination hydroxynitrile lyases and its application for being used to prepare optical homochiral cyanalcohol | 华东理工大学 | 2019-08-06 | — | — | CN | disclosed |
| EP-0001559-B1 | SYNTHESIS OF 2-KETO-1,4-DIAZACYCLOALKANES | The B.F. GOODRICH Company (US) | 1982-01-13 | — | — | EP | disclosed |
| US-4297497-A | Synthesis of 2-keto-1,4-diazacycloalkanes | THE B. F. GOODRICH COMPANY | 1981-10-27 | — | — | US | disclosed |
| EP-0029088-A2 | Synthesis of 2-keto-1,4-diazacycloalkanes | The B.F. GOODRICH Company (US) | 1981-05-27 | — | — | EP | disclosed |
| EP-0024337-A1 | Synthesis of 2-keto-1,4-diazacycloalkanes | The B.F. GOODRICH Company (US) | 1981-03-04 | — | — | EP | disclosed |
| US-4167512-A | Synthesis of 2-keto-1,4-diazacycloalkanes | THE B. F. GOODRICH COMPANY (US) | 1979-09-11 | — | — | US | disclosed |
| EP-0001559-A2 | Synthesis of 2-keto-1,4-diazacycloalkanes | The B.F. GOODRICH Company (US) | 1979-05-02 | — | — | EP | disclosed |