Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21634806 | 1.00 | MAOA (0.56) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL21634805 | 0.92 | MAOA (0.56) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL28562144 | 0.92 | MAOA (0.56) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL21634836 | 0.90 | MAOA (0.61) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL21634838 | 0.90 | MAOA (0.61) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL21634794 | 0.89 | MAOA (0.72) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL4171317 | 0.84 | MAOA (0.60) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL21635096 | 0.84 | MAOA (0.56) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL4883403 | 0.83 | MAOA (0.58) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL18410309 | 0.83 | MAOA (0.77) | MAOAMAOBCYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020021468-A1 | SUBSTITUTED OXAZOLIDINONES FOR THE TREATMENT OF MAMMALIAN INFECTIONS | CADILA HEALTHCARE LIMITED (IN) | 2020-01-30 | — | — | WO | claimed |
| WO-2020021468-A1 | SUBSTITUTED OXAZOLIDINONES FOR THE TREATMENT OF MAMMALIAN INFECTIONS | CADILA HEALTHCARE LIMITED (IN) | 2020-01-30 | — | — | WO | disclosed |